Combo Amnion and Wharton's Jelly

As low as $795.00
In stock
SKU
Combo Amnion and Wharton's Jelly

Combo Amnion & Wharton’s Jelly (Amniotic membrane and Wharton’s Jelly)

The Amnion is a human tissue allograft derived from placental tissue - amniotic membrane and Wharton’s Jelly (WJ) - derived MSCs sourced by minimal manipulation from the same donor tissue in accordance with FDA regulations. The combination of these cells not only dramatically increases the number of MSCs (mesenchymal stem cells) per sample, but the added power of WJ-derived MSCs adds the option for greater immune modulation when and where the patients need it most. This allograft product contains cellular material including fibroblasts, stem cells, Exosomes with MicroRNA and many growth factors/proteins. These growth factors play a role in tissue regeneration, cartilage repair, reducing the inflammatory response and creating new vasculature which increases blood flow. Additionally, the product includes the bio-scaffold which is the ECM that holds all of our cells together and provides high levels of collagen substrates, fibronectin and laminin which are key to developing normal healthy functioning tissue.

Combo Amnion & Wharton’s Jelly (Amniotic membrane and Wharton’s Jelly)

The Amnion is a human tissue allograft derived from placental tissue - amniotic membrane and Wharton’s Jelly (WJ) - derived MSCs sourced by minimal manipulation from the same donor tissue in accordance with FDA regulations. The combination of these cells not only dramatically increases the number of MSCs (mesenchymal stem cells) per sample, but the added power of WJ-derived MSCs adds the option for greater immune modulation when and where the patients need it most. This allograft product contains cellular material including fibroblasts, stem cells, Exosomes with MicroRNA and many growth factors/proteins. These growth factors play a role in tissue regeneration, cartilage repair, reducing the inflammatory response and creating new vasculature which increases blood flow. Additionally, the product includes the bio-scaffold which is the ECM that holds all of our cells together and provides high levels of collagen substrates, fibronectin and laminin which are key to developing normal healthy functioning tissue.

Promotes healing of these indications

  • Tennis Elbow
  • Golfer’s Elbow
  • Back Pain
  • Rotator Cuff
  • Osteoarthritis
  • Ligament Injury
  • Tendinopathies such as Achilles Tendinitis
  • Fasciopathies such as Plantar Fasciitis
  • Degenerative Disc Disease
  • Wounds, burns and fracture healing


Laboratory Analysis Results

  • This allograft product was tested by DaVinci Laboratories
  • There were no Red Blood Cells (RBC’s)
  • There were high levels of viable cells post cryopreservation and thaw
  • High levels of fibroblasts, MSCs with CD markers 73 and 90 which are indicative of their fetal nature and pluripotential capabilities
  • 82% of cells positive for fibroblast cell marker S100-A4
  • 23.9% of cells positive for MSCs marker CD90
  • .3% of cells positive for Keratinocyte marker Cytokeratin7
  • High levels of VEGF, PDGF-BB, bFGF, IL-1-ra



Advantages of allograft Allograft does not use plasmalyte to dilute the fluid It does not centrifuge the proteins out and then re-hydrate them in plasmalyte Our product is purified amniotic membrane maintaining all of the messengers: growth factors, exosomes, and microRNA By using only amniotic fluid as its base, our allograft product maintains the highest levels of HA compared to competitors

This Combination (Amniotic Membrane and Wharton’s Jelly combined) utilizes the amniotic membrane (AM) which is a thin fetal tissue inside of the fetal placenta that is made up of the epithelium, basement membrane and stroma. Extracted in a sterile environment during elective cesarean sections, they are screened for communicable diseases and treated with broad-spectrum antibiotics for future implementation.
AM can give rise to several different cell types through its pluripotent properties, making its anti-angiogenic and pro-apoptotic features valuable for procedures related to ocular surface reconstruction, skin application and tissue engineering. The membrane’s application in tissue transplantation in particular is complimented by its anti-inflammatory, anti-bacterial, anti-viral and immunological characteristics.
For its use in ocular surface reconstruction, AM acts as a barrier to protect epithelium and offer pain relief from the eyelids causing friction. It’s basement membrane aids in the operation by inhibiting cell death and promoting epithelial growth via cell adhesion and migration. AM’s stroma makes use of its fetal hyaluronic acid to inhibit fibroblast growth, and decreasing inflammation by reducing cytokines.
Because the structures behind AM place emphasis on wound healing and are non-tumorigenic, they can also be applied to oncology. Its combative reaction to tumor growth can prevent nutrients and oxygen from being delivered to cancer cells, interfering with a tumor’s development. By obstructing a tumor’s angiogenesis, growth, and metastasis, as well as promoting tissue growth the amniotic membrane can be further utilized in both creating new tissue and treating tumors in an ethical and innovative manner.

Write Your Own Review
You're reviewing:Combo Amnion and Wharton's Jelly
Icon Label Description Type Size Download
Cartilage Repair in the Knee Cartilage Repair in the Knee Using Umbilical Cord Wharton's JellyeDerived Mesenchymal Stem Cells Embedded Onto Collagen Scaffolding and Implanted Under Dry Arthroscopy pdf 1006.9 KB Download
Growth Factors and Cellular Components Cryopreserved Amniotic Fluid/Membrane/Wharton’s jelly graft bioassay; Indications for use in regenerative therapeutics pdf 398.2 KB Download
Combating Osteoarthritis through Stem Cell Therapies Knee osteoarthritis (OA) is a chronic degenerative disorder which could be distinguished by erosion of articular cartilage, pain, stiffness, and crepitus. Not only aging-associated alterations but also the metabolic factors such as hyperglycemia, dyslipid pdf 2.3 MB Download
x

Chat With Us

Copyright © 2013-present Medicus LLC All rights reserved.